Professor Georg Bartsch, MD

Professor and Chairman of the Department of Urology

Date of Birth: 5. Juli 1942

Place of Birth: Innsbruck

Innsbruck Medical University

6020 Innsbruck, Innrain 52

Tel: 0512/504-24811

Fax: 0512/504-28365

e-mail: georg.bartsch@uibk.ac.at

Vice-President in charge of matters pertaining to the University Clinics in accordance with the statutes of the University Law UG 2002:
11/2003 to 9/2007

Academic career

1961 to 1967 Medical studies at the School of Medicine, Innsbruck University

1963 to 1967 Demonstrator at the Anatomy Institute, School of Medicine, Innsbruck University

1965 Externship, Southern General Hospital, Glasgow, Scotland

1967 Graduation from the School of Medicine, Innsbruck University (M.D.)

1967 to 1970 Assistant at the Institute of Pathology, Innsbruck University

1971 to 1977 Residency at the Department of Urology, Innsbruck University Hospital, Innsbruck University

1978 Habilitation

1978 Call to the Chair (Chef de Clinique) at the Department of Urology, Rotterdam University; declined after negotiations

1978 Research stay at Johns Hopkins University, Baltimore, USA

From 1980 Assistenzarzt Associate Professor at the Department of Urology, Innsbruck University Hospital, Innsbruck University

1980 Research stay at Johns Hopkins University, Baltimore, USA

1980 Call to the Chair Department of Urology at Victoria Hospital, McGill University Montreal; declined after negotiations

1981 and 1983 Research stays at Johns Hopkins University, Baltimore, USA

1983 Research stay at Roswell Park Memorial Institute, Buffalo, USA and the George Washington University, St. Louis, USA

1984 Research stay at Johns Hopkins University, Baltimore, USA

1985 Call to the Chair, Department of Urology, Toronto Western Hospital, Toronto, Canada; declined after negotiations

1985 Call to the Chair, Department of Urology, Amsterdam University (Academish Ziekenhuis, Academish Medisch Zentrum); declined after negotiations

1986 Research stay at the University of Southern California, Norris Cancer Hospital, Los Angeles, USA

Since 1986 President of the European Association of Oncology and Endocrinology in Urology

Since 1987 Chairman of the Department of Urology, Innsbruck University Hospital

Since November 2003 Vice-President in charge of affairs pertaining to the Clinics of the Innsbruck Medical University

Awards

1977 Award of the Hoechst-Stiftungs A.G., University Innsbruck (jointly with H. Hindermann and H. P. Rohr) for: THE EFFECT OF A SYNTHETIC PROGESTINE OF THE FINE STRUCTURE OF RAT PROSTATE (ULTRASTRUCUTRAL-MORPHOMETRIC ANALYSIS). Experimental and Molecular Pathology 23 (1975), 188-202

1977 Award of the European Association of Urology for: STEREOLOGY, A NEW QUANTITATIVE MORPHOLOGICAL APPROACH TO STUDY PROSTATIC FUNCTION AND DISEASE. European Urology 3/2 (1977), 85-95, Habilitation thesis

1978 C. E. Alken Award (jointly with H. P. Rohr) for: DIE BEDEUTUNG DES STROMAS BEI DER THOMORPHOGENESE DER MENSCHLICHEN PROSTATAHYPERPLASIE. Aktuelle Urologie 10 (1979), 137

1980 Award of the Medical Chamber of Tyrol und Vorarlberg (jointly with M. Oberholzer, O. Müller und H. P. Rohr) for: LIGHT MICROSCOPIC ANALYSIS OF THE NORMAL HUMAN PROSTATE AND OF HUMAN BENIGN PROSTATIC HYPERPLASIA. Journal of Urology 1979, 487-491

1992 Maximilian Nitze Prize of the German Association of Urology for: POINT MUTATION IN THE DNA BINDING DOMAIN OF THE ANDROGEN RECEPTOR IN TWO FAMILIES WITH REIFENSTEIN SYNDROME

1994 Großhadern Prize for Innovation in Urology for: ANDROGENREZEPTORVERÄNDERUNGEN BEI STÖRUNGEN DER MÄNNLICHEN GESCHLECHTSDIFFERENZIERUNG UND BEIM PROSTATAKARZINOM

1994 Heinrich Warner Prize for: ACTIVATION OF ANDROGEN RECEPTOR IN PROSTATIC TUMOR CELL LINES BY IGF-1, KGF AND EGF

1996 Reinhold Witzel Prize for: METASTASES FROM PROSTATIC CARCINOMA EXPRESS ANDROGEN RECEPTOR PROTEIN

1997 ARTP Prize (French Association for Prostate Tumor Research) for: ANDROGEN RECEPTOR DELETION MUTANTS IN THE CROSS-TALK BETWEEN ANDROGEN AND POLYPEPTIDE SIGNALING PATHWAYS

1998 Gunther E. Voges Prize for: ANDROGEN ABLATION IN LNCaP CELL LEADS TO AN INCREASE IN ANDROGEN RECEPTOR ACTIVITY AND REDUCED TGF-ß RESPONSIVENESS und für: UP-REGULATION OF ANDROGEN RECEPTOR ACTIVITY BY INTERLEUKIN-6 IN PROSTATE CANCER CELLS

2001 EAU Best Published Urological Paper Prize for: INHIBITION OF LNCaP PROSTATE CANCER CELLS BY MEANS OF ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES

2001 Harry Metcalf Spence Medal of the American Association of Genitourinary Surgeons

Awards for scientific exhibitions

1978 Deutsche Gesellschaft für Urologie (together with G. Flora, R. Buchsteiner and L. Riedler) for: Traumatische Nierenarterienthrombose, Diagnostik und Therapie

1979 American Urological Association (jointly with A. Schmassmann, G. Mikuz and H. P. Rohr) for: Quantification of human sperm morphology and motility by means of semi-automatic image analysis systems

1979 The Société Internationale d'Urologie (S.I.U.)(International Association of Urologists) (jointly with H. P. Rohr) for: Morphological investigations on the prostate

1982 European Association of Urology (jointly with U. Stanzl and H. Hintner) for: Types of Collagens (I, II, IV) and Laminin in the normal and hyperplastic human prostate (immunofluorescence study)

1983 American Urological Association (jointly with U. Schweikert and J. Glatzl) for: Diagnosis and Management of Male Pseudohermaphroditism

1986 BARD Award, German Association of Urology (jointly with W. Schachtner, K. Colleselli and S. Poisel) for: Nerverhaltende bilaterale retroperitoneale Lymphadenektomie - anatomische Studie, Zugangsweg und Operation

Memberships

Austrian Association of Urology

German Association of Urology

German Association of Endocrinology

European Association of Urology

American Association of Urology

American Association of Fertility

Comité Internacional de Andrologia (CIDA)

European Society of Endocrinology and Oncology in Urology

Urological Research Society

International Society of Urology (SIU)

British Association of Urological Surgeons

Editor

THE PROSTATE (Alan R. Liss)

WORLD JOURNAL OF UROLOGY (Springer)

UROLOGIA INTERNATIONALIS (Karger)

UROLOGICAL RESEARCH (Springer)

UROLOGE A (Springer)

BRITISH JOURNAL OF UROLOGY International (Blackwell Science Ltd.)

Selected Publications

G. Bartsch, J. Frick, O. Holliger, M. Oberholzer, H. P. Rohr: Electron microscopic analysis of the normal human prostate and of benign prostatic hyperplasia, J. of Urology 1979, S. 481-486

G. Bartsch, M. Oberholzer, O. Muller, H. P. Rohr: Light microscopic analysis of the normal human prostate and of human benign prostatic hyperplasia, J. of Urology 1979, S. 487-491

H. Klocker, F. Kaspar, J. Eberle, S. Überreiter, Ch. Radmayr, G. Bartsch: Point Mutation in the DNA binding domain of the androgen receptor in two families with Reifenstein syndrome, Am. J. Hum. Genet. 50/6 (1992), S. 1318-1327

Z. Culig, A. Hobisch, M. V. Cronauer, A. C. Cato, A. Hittmair, C. Radmayr, J. Eberle, G. Bartsch, H. Klocker: Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone, Mol. Endocrinol. 7/12 (1993), S. 1541-1550

Z. Culig, A. Hobisch, M. V. Cronauer, C. Radmayr, J. Trapman, A. Hittmair, G. Bartsch, H. Klocker: Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor, Cancer Res. 54/20 (1994), S. 5474-5478

A. Hobisch, Z. Culig, C. Radmayr, G. Bartsch, H. Klocker, A. Hittmair: Distant metastases from prostatic carcinoma express androgen receptor protein, Cancer Res. 55/14 (1995), S. 3068-3072

A. Reissigl, G. Janetschek, J. Eberle, K. Colleselli, S. Weimann, J. Schwanninger, G. Bartsch: Renal cell carcinoma extending into the vena cava: surgical approach, technique and results, Br J Urol. 75 (1995), S. 138-142

W. Horninger, H. Unterlechner, H. Strasser, G. Bartsch: Transurethral prostatectomy: mortality and morbidity, Prostate. 28 (1996), S. 195-200

C. Rieser, G. Block, H. Klocker, G. Bartsch, M. Thurnher: Prostaglandin E2 and tumor necrosis factor alpha cooperate to activate human dendritic cells: synergistic activation of interleukin 12 production, J. Exp. Med. 186/9 (1997), S. 1603-1608

L. Höltl, C. Rieser, C. Papesh, R. Ramoner, G. Bartsch, M. Thurnher: CD83+ blood dendritic cells as a vaccine for immunotherapy of metastatic renal cell cancer, Lancet 352/9137 (1998), S. 1358

A. Stenzl, M. Ninkovic, D. Kolle, R. Knapp, H. Anderl, G. Bartsch: Restoration of voluntary emptying of the bladder by transplantation of innervated free skeletal muscle, Lancet 351/9114 (1998), S. 1483-1485

C. Rieser, C. Papesh, M. Herold, G. Block, R. Ramoner, H. Klocker, G. Bartsch, M. Thurnher: Differential deactivation of human dendritic cells by endotoxin desensitization: role of tumor necrosis factor alpha and prostaglandni E2, Blood 91/9 (1998), S. 3112-3117

H. Strasser, M. Tiefenthaler, M. Steinlechner, G. Bartsch, G. Konwalinka: Urinary incontinence in the elderly and age-dependent apoptosis of rhabdosphincter cells, Lancet 354/9182 (1999), S. 918-919

D. Strohmeyer, D. Rossing, A. Bauerfeind, O. Kaufmann, H. Schlechte, G. Bartsch, S. Loening: Vascular endothelial growth factor and its correlation with angiogenesis and p53 expression in prostate cancer, Prostate. 45 (2000), S. 216-224

F. Frauscher, A. Klauser, E. J. Kalpern, W. Horninger, G. Bartsch: Detection of prostate cancer with microbubble ultrasound contrast agent, Lancet 357/9271 (2001), S. 1849-1850

A. Stenzl, M. Ninkovic, N. Ashammakhi, I. E. Eder, G. Bartsch: Reconstruction of the lower urinary tract. Developments at the beginning of a new century, Urologe A 40 (2001), S. 368-375

M. Thurnher, C. Zelle-Rieser, R. Ramoner, G. Bartsch, L. Holtl: The disabled dendritic cell, Faseb J. 15 (2001), S. 1054-1061